Simonetta, Ludovico, an Italian cardinal, was born at Milan early in the 16th century. After having received the diploma of doctor in utroque jure (1535), he entered holy orders, and succeeded his uncle Giacomo as bishop of Pesaro in 1536. In 1560 he was called to the episcopal see of Lodi, and was made cardinal in 1561, and in 1564 one of the legates at the Council of Trent. He died at Rome, April 30, 1568. There is preserved in the Ambrosian Library at Milan part of his Correspondence with Charles Borromeo, whose friend he was.