Makrina The Roman Catholic Church recognizes two saints by this name.
1. A Cappadocian lady, grandmother of Gregory of Nyssa, who suffered persecution under the reign of Maximian, and wandered for a long time through the woods, together with her husband. She is commemorated on the 14th of January.
2. The sister of St. Basil and of St. Gregory of Nyssa; after the death of her father she withdrew into solitude, and afterwards induced her mother to establish a convent in Pontus, into which she retired. She died in 379, after performing a great number of miracles, etc. Her life was written by her brother, St. Gregory. She is commemorated on the 19th of July. — Herzog, Real-Encyklop. 8:746; Pierer, Universal-Lexikon, 10:764; Migne, Nouv. Encyclopedie Theologique, 2:1298.