Clayton, Isaac, an English Wesleyan minister, was born at Daisy Hill, near Bradford, Yorkshire, May 22, 1778. He was of pious parentage; was converted in 1793; sent to the Otley Circuit in 1800; admitted on trial at the conference of 1801, and travelled the Thetford, St. Neots, Northampton, Sevenoaks, London, Dover, Sheffield, Huddersfield, Keighley, Barnsley, and eight other circuits, the last being Cleckheaton. He died at Bradford, Oct. 23,1833. Mr. Clayton was spiritual-minded, faithful, and conscientious. See Minutes of the British Conference, 1834; Wesl. Meth. Mag. 1836, p. 81 sq.