Caine, John a Methodist Episcopal minister, was born on the Isle of Man, Oct. 16, 1812. He emigrated to America at the age of sixteen; experienced conversion three years later; and, after laboring some time as a local preacher, he, in 1844, entered the Genesee Conference, in which he labored as health permitted to the close of his life, in 1853. Mr. Caine was excessive in good works, and, abundantly successful. He was ardent in piety, punctual in duty, and true to Christ. See Minutes of Annual Conferences, 1853, p. 252.