Brison was a eunuch of the empress Eudoxia, an orthodox Christian, and a faithful friend of Chrysostom. He took the lead in the processions set on foot to overpower the services of the Arians, and in an assault made by them received a serious wound in the head from a stone. When, on Chrysostom's first deposition, Eudoxia's fears had been aroused by the earthquake, Brison was one of the messengers sent to discover the archbishop's place of retreat. He found him and brought him back. On his arrival at Cucusus, Chrysostom wrote to Brison, giving an account of his journey and its miseries.