Fiesco, Giorgio an Italian prelate, was archbishop of Genoa when pope Eugenius IV appointed him cardinal-priest, with the title of St. Anastasia, and bishop of Ostia. Nicholas V gave him the legation of Liguria. Giorgio Fiesco enjoyed the favor of Calixtus III and of Pius II. He died at Rome, October 11, 1461, but his body was transferred to Genoa. See Hoefer, Nouv. Biog. Generale, s.v.